Karin Edler

SEK 0.00

Principal Investigator
Karin Edler works as a professor at the Centre for Analysis and Synthesis at the Science Faculty at Lund University.

Project in final call:

High throughput SAXS for visualising solid lipid nanoparticles on COSAXS beamline at MAX IV

Principal Investigator
Karin Edler works as a professor at the Centre for Analysis and Synthesis at the Science Faculty at Lund University.

Project in final call:

High throughput SAXS for visualising solid lipid nanoparticles on COSAXS beamline at MAX IV

Research with Karin Edler

Work in the Edler group focuses on understanding the formation of functional hierarchically structured materials in order to apply that understanding to make new materials. We use self-assembly, driven by interactions between nanoscopic species (micelles, nanoparticles, polymers) in solution and at interfaces to form materials with organized structures from nm to cm. Understanding interactions between surfaces, nanoparticles and other species is central to our control over structure and thus function.

We use time-resolved grazing incidence X-ray & neutron reflectivity, liquid diffraction and small angle scattering to study formation mechanisms & final structures. A range of other complementary techniques (including TEM, SEM, AFM, NMR, light scattering, surface tension, conductivity, XRD, SESANS, USANS/USAXS, gas adsorption) are also used to characterise our materials across length scales from tens of Ångstroms to microns.

Extensive collaborations with other groups in industry and academia apply the novel materials synthesised in our group to applications from delivery of active species, to catalysis and “green” gels or emulsions.

AMBER postdoctoral fellowship project (final call)

High throughput SAXS for visualising solid lipid nanoparticles on COSAXS beamline at MAX IV

Lipid nanoparticles are rapidly transforming the field of drug delivery, including RNA therapeutics and precision medicine. Despite their importance, many fundamental questions remain about how nanoparticle structure governs encapsulation, stability, transport, and biological performance. This project aims to establish direct links between nanoscale structure and function in lipid nanoparticles using advanced synchrotron SAXS/WAXS methods at MAX IV.

The postdoctoral researcher will play a central role in developing new experimental and analytical capabilities for high-throughput lipid nanoparticle characterisation at CoSAXS. The work combines synchrotron experiments, advanced scattering analysis, and collaborative method development.

The successful candidate will:

  • design, plan, and perform SAXS/WAXS experiments on solid lipid nanoparticles and related soft matter systems

  • develop high-throughput workflows for nanoparticle characterisation at CoSAXS

  • investigate nanoparticle formation pathways, internal organisation, and structural evolution

  • analyse scattering data using advanced computational approaches, including atomistic and coarse-grained modelling

  • contribute to the development of data analysis tools for complex nanoparticle systems

  • participate in neutron and synchrotron experiments at international large-scale facilities

  • support relevant user experiments and contribute to the broader scientific activities of the beamline

  • train and support users in scattering workflows and analysis methods

  • contribute to supervision of student projects and collaborative research activities

  • disseminate research through publications, conference presentations, workshops, and international collaborations

The position offers a unique opportunity to contribute both to frontier research in nanostructured therapeutics and to the development of next-generation experimental methods for the wider scientific community.

Location: Lund, Sweden

Organisation: MAX IV Laboratory

Links

Read more about Karin Edler

AMBER call in EURAXESS main call (starting point for application)

Guide for applicants